Semaglutide vs Tirzepatide
Both are proven GLP-1 medications for weight loss. Here's how they compare — mechanism, results, side effects, and pricing.
| Feature | Semaglutide | Tirzepatide |
|---|---|---|
| Mechanism | GLP-1 receptor agonist | Dual GIP/GLP-1 agonist |
| Avg Weight Loss | 14.9% body weight | 22.5% body weight |
| Clinical Trial | STEP 1 (68 weeks) | SURMOUNT-1 (72 weeks) |
| Brand Names | Ozempic, Wegovy | Mounjaro, Zepbound |
| Dosing | 0.25mg → 2.0mg weekly | 2.5mg → 15mg weekly |
| REMEVi Price | From $249/mo | From $339/mo |
| Best For | Steady, proven results | Maximum weight loss |
How it works
Semaglutide mimics the GLP-1 hormone, reducing appetite and slowing gastric emptying. Clinical trials showed an average 14.9% body weight loss over 68 weeks.
Dosage
Starts at 0.25mg weekly, gradually increasing to 2.0mg over 16-20 weeks.
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Semaglutide
Tirzepatide
Includes: physician review, compounded medication, free shipping, bilingual coordinator, patient portal
Frequently Asked Questions
Tirzepatide (22.5% avg) showed greater weight loss than semaglutide (14.9% avg) in clinical trials. However, individual results vary and your physician will help determine the best option for you.
Yes, your REMEVi physician can help you transition between medications if needed. Some patients start with semaglutide and move to tirzepatide for enhanced results.
Both medications share similar GI side effects (nausea, constipation). Tirzepatide may have slightly higher rates initially due to dual mechanism, but most side effects are mild and temporary.
Tirzepatide is a newer, dual-mechanism medication with stronger clinical results. The higher cost reflects the more complex compounding process and stronger clinical profile.
Yes, both medications require a prescription from a licensed physician. REMEVi includes physician review in your monthly price — no separate consultation fee.
Not Sure Which Is Right for You?
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