Tirzepatide
Dual GLP-1 and GIP receptor agonist.
View treatment
Oral Semaglutide
Compounded semaglutide tablet · one a day · no injections
From $215/mo
The same GLP-1 molecule as the injection, in a tablet that dissolves between your cheek and gum once a day. No syringe, no sharps box, no refrigerator. A licensed provider reviews your intake, sets your titration, and adjusts it as your body changes.
Available in all 50 states and Washington, DC — your prescription comes from a provider licensed in your state.
- No insurance required
- Licensed U.S. providers
- Pharmacies we name
- Founded by patients
- Fast, discreet shipping
- Unlimited follow-up with your clinician
$0 Membership fees
Start the oral questionnaire Not sure? Compare tablet vs injection You choose your plan during the medical intake. Your per-month price never climbs with your dose.
Tablet vs injection
Made for people who won't do needles.
If a weekly injection is the reason you haven't started, this is the version for you: one tablet that dissolves between your cheek and gum, once a day. No syringe, no sharps box, no refrigerator, nothing to explain at the airport. Same licensed provider, same named pharmacy, same bilingual care team.
One thing we tell everyone: clinical protocols consider oral semaglutide generally less effective than the injection at the doses used. If you can inject, the injection is the stronger option — and switching later is a provider conversation, not a new sign-up.
It's for you if
- You'd rather not inject.
- You travel, or share a fridge.
- You want the simplest daily routine.
It's probably not for you if
- You want the strongest option and a weekly injection doesn't bother you — that's tirzepatide.
- Your provider needs a higher dose than the tablet offers.
Before you decide
What is compounded oral semaglutide — and is it safe?
The honest version, sourced, before any pricing.
Compounded oral semaglutide is semaglutide — a GLP-1 receptor agonist — prepared by a state-licensed compounding pharmacy as a small tablet that dissolves in the mouth. It is not a brand-name product and it is not FDA-approved; the brand-name oral versions exist and are prescribed differently.
What makes a compounded program safe is the oversight around it: a licensed provider reviewing your history, labs before prescribing, a named pharmacy you can look up, and a care team you can message when something feels off. Nausea, constipation and reduced appetite are the common early effects with any semaglutide; they are the reason doses step up slowly.
Content last updated: · Sources: The Lancet (OASIS 1), FDA compounding guidance, REMEVi clinical protocol. Read the full evidence review on our Science page.
How it works
Same molecule, taken a different way.
Oral semaglutide is the same GLP-1 receptor agonist as the injection. The tablet is designed to dissolve in the mouth so the medication is absorbed through the lining of the cheek rather than swallowed and broken down in the stomach.
Activates GLP-1 receptors
Semaglutide mimics the GLP-1 your gut releases after a meal, acting on the receptors that signal fullness to the brain.
Dissolves, doesn't get swallowed
An oral-dissolving tablet (ODT) is held between the cheek and gum until it dissolves. That route is why the compounded tablet uses lower milligram doses than a swallowed pill.
Steps up monthly
Treatment starts at 5 mg daily and moves to 10 mg about every four weeks, if your provider agrees — based on how you're doing, not on a calendar.
The evidence
What the trials measured — and what they didn't.
The largest trial of a once-daily oral semaglutide for weight management.
OASIS 1 randomised adults with obesity to once-daily oral semaglutide 50 mg or placebo for 68 weeks. Results are for the branded swallowed tablet studied in the trial, not for compounded oral-dissolving tablets and not for REMEVi patients — individual results vary.
−15.1% Mean body-weight change vs −2.4% on placebo
68 weeks Trial duration · n = 667 · 50 mg once-daily oral dose
Source: Knop FK et al. "Oral semaglutide 50 mg taken once per day in adults with overweight or obesity" (OASIS 1), The Lancet, 2023.
The dose is stepped up deliberately, not started high.
Treatment starts at the lowest strength and steps up roughly monthly if your provider agrees. Most gastrointestinal side effects track with how fast the dose rises rather than the final dose itself, which is why the schedule is set by a clinician and not by a calendar.
5 → 10 mg Monthly dose steps
1/day Held between cheek and gum · ~4 weeks between steps
Source: REMEVi clinical protocol; your provider adjusts the schedule to your response and tolerability.
OASIS 1 studied a branded 50 mg swallowed oral semaglutide tablet in adults with obesity; it did not study compounded oral-dissolving tablets, which use different doses and a different route. Trial figures describe the medication studied, not REMEVi patients, and are not a guarantee of individual results. Compounded medications are not FDA-approved.
How REMEVi works
Reviewed within 24 hours, shipped in one to three days.
See If You Qualify
A licensed provider decides whether treatment is appropriate — nobody is prescribed automatically.
-
Step 1Medical intake
A guided set of questions covering your history, current medications, and goals.
About 2 minutes -
Step 2Clinician review
A licensed provider in your state reviews your intake and prescribes only if it is clinically appropriate.
Within 24 hours -
Step 3Pharmacy and shipping
A named, state-licensed pharmacy fills your prescription and ships it in discreet packaging. Tablets ship at room temperature — no cold pack, no fridge.
Ships 1–3 days after approval -
Step 4Follow-up, in your language
Message your care team as often as you need for dose adjustments and side-effect support, in English or Spanish.
Unlimited, every month
Some states require a live audio or video consultation before a prescription can be approved, which can add a day or two.
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The clinical standard, without the needle.
Licensed U.S. providers
A clinician licensed in your state reviews every intake and sets your titration. No wait lists, no insurance required.
One flat price
Your per-month price never climbs with your dose. No membership fee, no lab fee, no dose upcharge.
Named pharmacies
We publish which state-licensed compounding pharmacies fill our prescriptions, and the name appears on your vial label.
Bilingual care
Real people on WhatsApp in English and Spanish — the reason REMEVi exists, not an add-on service tier.
The REMEVi Flat-Dose Guarantee
Your price never rises with your dose. Ever.
Most programs charge more as your dose increases. At REMEVi, your price stays flat at every dose — with no separate membership fee on top of the medication price.
THE 4 QUESTIONS EVERYONE ASKS
Named out loud, answered in full.
REMEVi's semaglutide is compounded by a state-licensed compounding pharmacy under its state board of pharmacy. Compounded medications are not FDA-approved finished drug products; they are prepared under the 503A framework to USP <797> sterility standards and prescribed by a licensed provider in your state who will review the risks, benefits, and considerations with you.
Pharmacy
State-licensed US compounding
Sterility standard
USP <797>
Active ingredient
Semaglutide
Provider network
All 50 states + DC
FAQ
Oral semaglutide questions answered
One tablet a day. Let it dissolve between your cheek and gum — don't chew or swallow it. Your provider's instructions cover timing; most people pick a fixed time and keep it.
5 mg and 10 mg oral-dissolving tablets. Treatment starts at 5 mg and steps up about every four weeks if your provider agrees.
Clinical protocols consider oral semaglutide generally less effective than injectable semaglutide at the doses used. For many people the trade is worth it; if you can inject, the injection is the stronger option. Your provider will tell you straight.
The same as any semaglutide: nausea, constipation, reduced appetite, sometimes reflux — mostly in the first weeks and at each dose step. Your care team is a message away, and your provider can slow the steps.
Yes, through your provider. Switching from oral to injectable starts at the injection's first dose level; it's a plan change inside your account, not a new sign-up.
No. It is prepared by a state-licensed compounding pharmacy under the 503A framework and is not an FDA-approved product. Brand-name oral semaglutide products exist and are prescribed separately.
Medication, provider evaluation and follow-ups, shipping, and support in English or Spanish. $215/mo on the 24-week plan, $229/mo on 12 weeks, $249 month to month. No membership fee; your price doesn't rise with your dose.
Yes — your provider reviews labs before prescribing and at intervals during treatment. Recent labs can be uploaded; otherwise we arrange them.
Disclaimer: This page is for educational purposes and is not medical advice, diagnosis or treatment. Compounded oral semaglutide is not FDA-approved and is not a generic version of any brand-name product. Your provider prescribes a compounded preparation only when they determine it offers a clinically significant difference for you — for example, personalised dose titration. Eligibility and prescriptions are determined solely by licensed medical providers using clinical judgement; not everyone qualifies. Trial figures describe the active medication studied, not REMEVi outcomes. Individual results vary.
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