Brand cost, checked
Zepbound vials (LillyDirect) self-pay price
As of October 8, 2026, a month of Zepbound single-dose vials from LillyDirect — four vials, 28 days — costs $299 at 2.5 mg, $399 at 5 mg and $449 at 7.5 to 15 mg, as long as each refill is bought within 45 days. Miss that window and 7.5 mg costs $499; higher doses, $699.
How much are Zepbound vials on LillyDirect?
Quick answer: $299 to $449 a month with on-time refills, by dose; up to $699 if a refill is late (as of October 8, 2026).
LillyDirect shows these as “starting at” prices for a month of vials. The 7.5–15 mg figure is Lilly’s Self Pay Journey price, which depends on refilling within 45 days; the regular price is in the last column. Lilly notes that 2.5 mg is a starting dose and is not approved as a maintenance dose. Source: LillyDirect Zepbound terms and conditions, checked October 8, 2026.
| Dose | Refill within 45 days | Refill after 45 days (regular) |
|---|---|---|
| 2.5 mg (starting dose) | $299 | $299 |
| 5 mg | $399 | $399 |
| 7.5 mg | $449 | $499 |
| 10 mg | $449 | $699 |
| 12.5 mg | $449 | $699 |
| 15 mg | $449 | $699 |
Additional taxes and fees may apply, per Lilly. Syringes and needles are not included.
What do you get for the monthly vial price?
Quick answer: Four single-dose vials — one per week, 28 days. Syringes and needles are not included; you buy them separately.
Each vial holds one weekly dose. You draw the dose into a syringe and inject it, so you need a syringe and needle for every dose. Ask your prescriber which syringe size to use and how to inject; LillyDirect’s terms say a needle and syringe purchase is required with the vial.
A “month” in Lilly’s pricing is always 28 days, not a calendar month, so a year of weekly doses is 13 boxes, not 12. Plan your budget on that count.
How do I buy Zepbound vials from LillyDirect?
Quick answer: With a prescription for the vial from a licensed prescriber, filled by LillyDirect. Vials are self-pay only and sold only there.
In order:
- Get a prescription that names the vial. A licensed prescriber decides whether Zepbound is appropriate for you and at which dose.
- Have it sent to LillyDirect. The vial is “exclusively available through LillyDirect” and “self-pay only,” per Lilly.
- Pay the self-pay price for your dose. Insurance is not billed for the vial.
- Buy syringes and needles. They are not in the box.
- From 7.5 mg, refill within 45 days. That keeps the Self Pay Journey price.
What happens if I refill Zepbound vials late?
Quick answer: On 7.5 mg and up, a refill bought more than 45 days after the last delivery costs the regular price: $499 or $699.
Lilly applies the $449 price automatically on your first purchase of a 7.5, 10, 12.5 or 15 mg vial. To keep it, each refill must be completed within 45 days of the delivery or pickup date of the previous fill. If not, that refill is charged at $499 for 7.5 mg or $699 for 10, 12.5 or 15 mg. Lilly may end or change the offer at any time.
Do Zepbound vials cost less than the KwikPen or Costco?
Quick answer: Not than the KwikPen on LillyDirect — same price. Costco sells only the KwikPen, at $499.22–$699.21 at pickup (as of October 8, 2026).
On LillyDirect, the vial and the KwikPen are priced the same at every dose. The difference is in supplies and handling: the KwikPen needs only pen needles. Elsewhere, Costco’s search showed the KwikPen only, GoodRx showed coupons from $299 (location not shown), and TrumpRx.gov listed the vial at the LillyDirect prices.
| What | Price (USD) | Per | Conditions | Source |
|---|---|---|---|---|
| Zepbound self-pay, 2.5 mg (LillyDirect) | $299 | per 1-month supply (28 days: 4 single-dose vials or 1 KwikPen) | Vial or KwikPen; self-pay only. 2.5 mg is a starting dose, not a maintenance dose. Taxes and fees may apply. | LillyDirect Zepbound terms and conditions |
| Zepbound Self Pay Journey price, 7.5–15 mg | $449 | per 1-month supply (28 days: 4 single-dose vials or 1 KwikPen) | Applied automatically on the first purchase of these doses (from February 23, 2026); kept only if each refill is completed within 45 days of the previous delivery. Otherwise the regular price applies. Lilly may end or change it at any time. | LillyDirect Zepbound terms and conditions |
| Zepbound KwikPen self-pay savings card, 7.5–15 mg | $449 | per 1-month fill (1 KwikPen; pay as low as) | Subject to the 45-day refill rule; up to 11 fills a year; card expires December 31, 2026. | LillyDirect Zepbound terms and conditions |
| Costco member price, Zepbound KwikPen 2.5–7.5 mg | $499.22 | per KwikPen, warehouse pickup | Costco members; home delivery costs slightly more. Only the KwikPen appears in Costco’s search (no vial). Costco does not say whether Lilly’s card can be used there. | Costco Member Value Pricing search |
| Costco member price, Zepbound KwikPen 10–15 mg | $699.21 | per KwikPen, warehouse pickup | Costco members; home delivery costs slightly more. | Costco Member Value Pricing search |
| Zepbound savings card, commercial plan that does not cover it | $499 | per 1-month fill (28 days, up to 4 single-dose pens; pay as low as) | Single-dose pen; needs commercial insurance that does not cover Zepbound and a prescription for an approved use; card expires December 31, 2026. Commercial insurance only; people with Medicare, Medicaid or other government coverage cannot use it. | LillyDirect Zepbound terms and conditions |
| GoodRx coupon, Zepbound (as low as) | $299 | per KwikPen, 2.5 mg (GoodRx default listing) | GoodRx coupon “as low as” price; the page does not show which pharmacy or location. Prices updated 10/08/26. | GoodRx |
| TrumpRx listing, Zepbound vial 2.5 mg | $299 | per month supply, out of pocket | Links to LillyDirect self-pay; 7.5–15 mg are listed at the on-time-refill price. | TrumpRx.gov |
| REMEVi — compounded tirzepatide (not a brand-name drug) | From $225 per 4 weeks on the 24-week plan · or $269 every 4 weeks, cancel any time | 4 weeks (28 days) | Compounded; not FDA-approved. A licensed provider decides whether to prescribe. One price at every dose; full refund if not prescribed. | REMEVi pricing |
Can I use insurance or a savings card for Zepbound vials?
Quick answer: No. LillyDirect sells vials as self-pay only. Insurance savings cards apply to the single-dose pen; the KwikPen has its own self-pay card.
If your commercial plan covers Zepbound, the single-dose pen with Lilly’s card can cost as little as $25 a fill — far less than any vial price. Check coverage before paying cash. How each card works is in Mounjaro, Zepbound and Wegovy savings cards explained, and all Zepbound options are in how much Zepbound costs without insurance.
What do LillyDirect’s price terms mean?
Quick answer: Self-pay means you pay without insurance; a month is 28 days; a refill is your next box; the Journey price is the on-time-refill price.
LillyDirect’s pages are in English. The terms that decide what you pay:
- Self-pay: you pay the pharmacy directly; insurance is not billed.
- Single-dose vial: one vial, one weekly dose; four per month.
- 1-month supply: 28 days, not a calendar month.
- Refill: your next purchase after the previous delivery.
- Self Pay Journey Program: the on-time-refill price for 7.5–15 mg.
- Starting dose: 2.5 mg, used to begin treatment, not to stay on.
Is there a compounded option?
Quick answer: Yes. REMEVi offers compounded tirzepatide, prescribed by licensed providers: From $225 per 4 weeks on the 24-week plan · or $269 every 4 weeks, cancel any time.
A compounded medication is prepared by a state-licensed pharmacy for one patient’s prescription. Compounded medication is not FDA-approved and is not a generic of Zepbound. The FDA does not review compounded drugs for safety, effectiveness or quality before they are sold. Brand names appear on this page only to orient you; REMEVi does not sell brand-name drugs.
At REMEVi, a licensed provider reviews your health questionnaire and decides whether a prescription is appropriate. Compounded tirzepatide: From $225 per 4 weeks on the 24-week plan · or $269 every 4 weeks, cancel any time. Each plan has one price at every dose and every renewal of that plan, with no membership fee, and you get a full refund if you are not prescribed.
To weigh it against other programs, read our dated comparison of GLP-1 telehealth programs; every REMEVi plan and term is on the pricing page.
Frequently asked questions
How many vials come in a month of Zepbound?
Four single-dose vials, one per week, for 28 days.
Are syringes included with Zepbound vials?
No. Lilly’s terms say a needle and syringe purchase is required.
Can I buy Zepbound vials at a regular pharmacy?
Lilly says the vial is available exclusively through LillyDirect, self-pay only.
Is the 2.5 mg vial price the long-term price?
No. 2.5 mg is a starting dose. Most maintenance doses are $449 with on-time refills, or $499–$699 without (as of October 8, 2026).
Is compounded tirzepatide FDA-approved?
No. Compounded medication is not FDA-approved and is not a generic of Zepbound.
See whether REMEVi fits you
Compounded tirzepatide: From $225 per 4 weeks on the 24-week plan · or $269 every 4 weeks, cancel any time.
Each plan has one price, the same at every dose and every renewal, with no membership fee. Compounded medication is not FDA-approved.
Not prescribed? Full refund. Cancel anytime.