How Much Does Zepbound Cost?

As of October 8, 2026, Zepbound costs $299 a month for the 2.5 mg starting dose and $399 for 5 mg on LillyDirect self-pay; 7.5–15 mg cost $449 if each refill is bought within 45 days, otherwise $499 or $699 (LillyDirect terms). Lilly’s list price is $499–$1,086.37 per fill (Lilly pricing).

How much does Zepbound cost without insurance?

Quick answer: $299 to $699 a month on LillyDirect, depending on dose, or $449 for 7.5–15 mg when you refill within 45 days, as of October 8, 2026.

Lilly sells Zepbound to self-pay buyers through LillyDirect as a single-dose vial or a KwikPen, at the same price per 28-day supply for either. The 2.5 mg dose is a starting dose, not a maintenance dose. Taxes and fees may apply. Source: LillyDirect Zepbound terms

Zepbound dose (vial or KwikPen)	Refill within 45 days	Refill after 45 days
2.5 mg	$299	$299
5 mg	$399	$399
7.5 mg	$449	$499
10 mg	$449	$699
12.5 mg	$449	$699
15 mg	$449	$699

Per 28-day supply on LillyDirect, checked October 8, 2026. The 45-day price is Lilly’s Self Pay Journey offer, which Lilly may change or end. Elsewhere, Costco’s member price search lists only the KwikPen, at $499.22 (2.5–7.5 mg) or $699.21 (10–15 mg) at pickup (Costco), and GoodRx shows coupons from $299 without naming a location (GoodRx).

How much does Zepbound cost with insurance?

Quick answer: With commercial coverage, as little as $25 a fill with Lilly’s savings card; if your commercial plan doesn’t cover the pen, as low as $499.

Zepbound savings card	You pay	Conditions	Source
Commercial plan covers the single-dose pen	$25	As little as, per 1-, 2- or 3-month fill; savings capped at $100 per 1-month fill and $1,300 a year	LillyDirect terms
Commercial plan does not cover the pen	$499	As low as, per 28-day fill of up to 4 single-dose pens	LillyDirect terms
KwikPen self-pay card	$299–$449	By dose; 7.5–15 mg follow the 45-day refill rule	LillyDirect terms

The cards expire December 31, 2026, and none can be used by people with Medicare, Medicaid or other government coverage. Checked October 8, 2026.

Why don’t Mounjaro and Zepbound cost the same?

Quick answer: Lilly sells Zepbound self-pay through LillyDirect but publishes no self-pay price for Mounjaro, whose list price is $1,112.16 per fill.

Mounjaro is indicated for type 2 diabetes; Zepbound has its own indications including weight management. Zepbound self-pay offers advertise a starting price of $299 for a four-week supply of 2.5 mg in a KwikPen or vials; this is a starting dose, not maintenance. Later costs depend on dose, device and refill terms. That offer does not establish a Mounjaro price. Check each manufacturer’s information, reviewed October 8, 2026. Source: Zepbound manufacturer savings terms Source: Mounjaro manufacturer cost information

Does Medicare change what I pay for Zepbound?

Quick answer: Possibly. CMS’s temporary Medicare GLP-1 Bridge has a $50 copay for eligible Part D members; Lilly’s savings cards exclude government coverage.

Coverage depends on the drug, diagnosis, plan formulary and prior authorization. Ask about the cost after your deductible and any required clinical documentation. Commercial savings and self-pay offers have different rules. Medicare GLP-1 Bridge is a temporary program for certain eligible beneficiaries beginning in July 2026; it does not mean automatic coverage for everyone. CMS: Medicare GLP-1 Bridge eligibility

What do REMEVi plans cost, and how are they billed?

Quick answer: REMEVi bills every four weeks, not by calendar month, and the 12- and 24-week plans are paid upfront. These are compounded preparations, not Zepbound.

REMEVi prices use four-week billing periods, which are not calendar months. The 12- and 24-week terms require the full total upfront. Lab work that the clinician requires for treatment is included.

Compounded preparation	Every 4 weeks	12 weeks: total upfront	24 weeks: total upfront
Injectable semaglutide	$199	$507 ($169/4 weeks)	$954 ($159/4 weeks)
Injectable tirzepatide	$269	$699 ($233/4 weeks)	$1,350 ($225/4 weeks)
Compounded oral semaglutide	$249	$687 ($229/4 weeks)	$1,290 ($215/4 weeks)

See current semaglutide and tirzepatide plan details. Compounded oral semaglutide is not an approved Wegovy, Ozempic or Rybelsus tablet. Eligibility and prescribing depend on clinical evaluation. Service is available in 49 states and Washington, DC, excluding Louisiana.

Is compounded tirzepatide FDA-approved?

Quick answer: No. Compounded preparations are not FDA-approved, are not generics of Zepbound or any brand, and have no established clinical equivalence to them.

Compounded preparations are not FDA-approved, are not generics of the brands and do not have established clinical equivalence to them. FDA recommends their use only when an available approved product cannot meet the medical need. A lower price does not establish equal safety or effectiveness. Source: FDA: unapproved GLP-1 medicines

What should I check before choosing?

Quick answer: The product, route, pharmacy, supply length, full upfront payment, refill terms and cancellation policy — and who handles side effects.

Confirm the product, route, pharmacy, supply length, full upfront payment, refill terms and cancellation policy. Ask who handles side effects and what happens if clinical review does not recommend treatment. Review care options.